Sample Preparation

Sample preparation is an essential prelude for structural and molecular biology studies, as well as for biotechnology and drug discovery application, which can be particularly challenging in the case of eukaryotic proteins and complexes.  Instruct offer state-of-the-art infrastructures for the expression and production of biomolecules and their complexes in prokaryotic and eukaryotic systems .

Crystallisation

Crystallisation:

Crystallisation allows the 3D structure of macromolecules to be revealed through X-ray diffraction. Some molecules form crystals easily, others require more sophisticated techniques to generate the repeating structures necessary for analysis. Instruct offer a fully automated crystallisation pipeline to achieve high-throughput with short crystallisation plate processing times, high reproducibility, and increased efficiency of the screening process.

Nanobody Discovery

Nanobody Discovery:

Nanobodies are single chain antibodies which have revolutionary applications in structural biology. Our Nanobody Discovery service is accessible to all Instruct researchers.

Protein Production

Protein Production:

Instruct's services include protein expression, cloning and high throughput expression, and protein purification. Our techniques allow for expression of challenging proteins along with expert protein purification systems.