Claudia Alen Amaro

Project Manager

University of Oxford

BiochemistryMolecular BiologyMicrobiologyResearch ManagementProject ManagementResearch CommunicationEuropean Funding

Instruct Project Manager since the start of the project as a FP7 Capacities Project coordinated from the University of Oxford (May 2008). Now Instruct is in its operational phase and our office manages the provision of access to infrastructure to structural biologists around Europe. We also organise Instruct training program including courses and internships and R&D pilot project awards. We organise consortium meetings as well the Instruct Biennial Structural Biology Meeting. Before Instruct, I was the project manager for the FP6 Integrated Project GABRIEL coordinated by Imperial College, London. My role as project manager includes facilitating the communication between the partners, other scientific institutions and stakeholders and the European Commission. I organise meetings and workshops, administer the training events, and generally manage the running of the project. I coordinated the writing of annual reports to the European Commission. My experience with European Framework projects started in 2005 with the SPINE project (5th EC Framework Programme) coordinated by the Wellcome Trust Centre for Human Genetics, University of Oxford.

Before working as a project manager I worked for many years as a molecular biologist. I was a postdoctoral scientist at the Sir William Dunn School of Pathology (Oxford University) for 5 years working on the connection between chromatin remodelling and transcription. In my first years of research, my work was focused in the study of protein-DNA and protein RNA interactions, working with Bacillus subtilis in my two years postdoctoral fellowship at Tufts University (Boston, USA).

I obtained my first degree in Chemistry and Master in Pharmaceutical Chemistry in the Universidad Mayor de la República Oriental del Uruguay and my D. Phil in Biochemistry under the supervision of Prof. David Sherratt at the University of Oxford.

A role for chromatin remodeling in transcriptional termination by RNA polymerase II. Alén C, Kent NA, Jones HS, Aranda A, Proudfoot NJ Mol. Cell 2002 Dec; www.ncbi.nlm.nih.gov/pubmed/12504018
Bacillus subtilis aconitase is an RNA-binding protein. Alén C, Sonenshein AL Proc. Natl. Acad. Sci. U.S.A. 1999 Aug; www.ncbi.nlm.nih.gov/pubmed/10468622
RNA polymerase I in yeast transcribes dynamic nucleosomal rDNA. Jones HS, Kawauchi J, Braglia P, Alen CM, Kent NA, Proudfoot NJ Nat. Struct. Mol. Biol. 2007 Feb; www.ncbi.nlm.nih.gov/pubmed/17259992
Transcriptional termination by RNA polymerase I requires the small subunit Rpa12p. Prescott EM, Osheim YN, Jones HS, Alen CM, Roan JG, Reeder RH, Beyer AL, Proudfoot NJ Proc. Natl. Acad. Sci. U.S.A. 2004 Apr; www.ncbi.nlm.nih.gov/pubmed/15073335
The ArcA/ArcB two-component regulatory system of Escherichia coli is essential for Xer site-specific recombination at psi. Colloms SD, Alén C, Sherratt DJ Mol. Microbiol. 1998 May; www.ncbi.nlm.nih.gov/pubmed/9632255
Direct interaction of aminopeptidase A with recombination site DNA in Xer site-specific recombination. Alén C, Sherratt DJ, Colloms SD EMBO J. 1997 Sep; www.ncbi.nlm.nih.gov/pubmed/9311979
The first molecular characterization of tetracycline-resistant Neisseria gonorrhoeae from Uruguay. Marquez C, Xia M, Borthagaray G, Alen C, Acevedo A, Castro M, Dillon JA, Roberts MC J. Antimicrob. Chemother. 1996 Apr; www.ncbi.nlm.nih.gov/pubmed/8722552