Integrated Structural Bioinformatics - Efficient Algorithms for Large Biomolecular Structure Modeling
The platform presents a suite of servers to perform protein-protein docking. The method can handle (major) hinge based flexibility as well as minor conformational changes in the interface. A key advantage of the methodology is its computational speed allowing online processing.
An Algorithm For Protein Hinge Prediction Using Elastic Network Models
Rigid protein-protein soft Docking Algorithm Based on Shape Complementarity Principles
Molecular Docking Refinement Algorithm optimizing Side Chain fit and allowing minor Backbone Flexibility
Prediction of Complexes with Cn Symmetry by Geometry Based Docking
Multifit: Fitting of multiple proteins into their assembly density map
The INSTRUCT Bioinformatics Center develops efficient algorithms for protein structure and function prediction.It has one of the leading platforms in the modeling of protein-protein interfaces and is actively developing state of the art computational techniques for the integrative modeling of large multimolecular assemblies based on experimental data from various sourcesThe algorithms developed by the Center are among the fastest available and, usually, enable online processing of the data.